custom-made hyperdrive array fitted with a 16-tetrode electronic interface board eib-36-16tt  (Neuralynx inc)

Journal: eLife

Article Title: Feedback inhibition underlies new computational functions of cerebellar interneurons

doi: 10.7554/eLife.77603

Figure Lengend Snippet: ( a ) Sagittal section of the cerebellum showing tetrode tracks and the final location (red points) of tetrodes that recorded eyelid molecular layer interneurons (MLIs) and eyelid Purkinje cells (PCs). The custom-made hyperdrive array is shown above the cerebellar section. ( b ) Example of single units being isolated from a multi-unit recording with cluster cutting. The individual clusters and waveforms are color-coded to illustrate how unique features of the waveform across the four channels of the tetrode can be used to isolate single units from the multi-unit recording. ( c ) An example of a single conditioned eyelid response trial where the different response measures are color-coded according to the position of the eyelid in the rabbit. Gray shading indicates the duration of the conditioned stimulus and the black line represents the position of the eyelid throughout the trial. The conditioned response is delayed relative to stimulus onset and peaks at the end of the interstimulus interval (ISI). Different response measurements are color-coded according to eyelid position (right).

Article Snippet: A custom-made hyperdrive array (12 or 16 tetrodes, 2 references) fitted with an electronic interface board (EIB-54 or EIB36-16TT, Neuralynx) was implanted in the left anterior lobe of the cerebellar cortex at 17.8 mm ventral to lambda.

Techniques: Isolation